Beware Of Your Obesity..!!

A new study finds obese people have 8 percent less brain tissue than normal-weight individuals. Their brains look 16 years older than the brains of lean individuals, researchers said today.

Those classified as overweight have 4 percent less brain tissue and their brains appear to have aged prematurely by 8 years.

The results, based on brain scans of 94 people in their 70s, represent "severe brain degeneration," said Paul Thompson, senior author of the study and a UCLA professor of neurology.

"That's a big loss of tissue and it depletes your cognitive reserves, putting you at much greater risk of Alzheimer's and other diseases that attack the brain," said Thompson. "But you can greatly reduce your risk for Alzheimer's, if you can eat healthily and keep your weight under control."

The findings are detailed in the online edition of the journal Human Brain Mapping.

Obesity packs many negative health effects, including increased risk of heart disease, Type 2 diabetes, hypertension and some cancers. It's also been shown to reduce sexual activity.

More than 300 million worldwide are now classified as obese, according to the World Health Organization. Another billion are overweight. The main cause, experts say: bad diet, including an increased reliance on highly processed foods.

Obese people had lost brain tissue in the frontal and temporal lobes, areas of the brain critical for planning and memory, and in the anterior cingulate gyrus (attention and executive functions), hippocampus (long-term memory) and basal ganglia (movement), the researchers said in a statement today. Overweight people showed brain loss in the basal ganglia, the corona radiata, white matter comprised of axons, and the parietal lobe (sensory lobe).

"The brains of obese people looked 16 years older than the brains of those who were lean, and in overweight people looked 8 years older," Thompson said.

Obesity is measured by body mass index (BMI), defined as the weight in kilograms divided by the square of the height in meters. A BMI over 25 is defined as overweight, and a BMI of over 30 as obese.

The research was funded by the National Institute on Aging, National Institute of Biomedical Imaging and Bioengineering, National Center for Research Resources, and the American Heart Association.

Source : http://news.yahoo.com/s/livescience/20090825/sc_livescience/obesepeoplehaveseverebraindegeneration

Gaucher Disease

Gaucher disease, what is that?
Gaucher is a metabolic disease. It happens when our body cannot terminate 'trash' that normally sholud be 'broke out'into pieces, but it still remains inside.It happens because of lack of Enzym Glucocerebricidase. Later, this 'trash' will spread bad effects to our body such as Splenomegaly, Hepatomegaly, Anemia, bone pain, bone that easy to fracture, or even developmental delay.
Gaucher disease is inherited disease, most of patient are Ashkenazi Jews. There are three types of Gaucher disease. Type 1, type 2 and type 3. Those are distinguished by their clinical features, course, and ethnic predilection.

The clinician will diagnose Gaucher disease by doing some investigations such as Enzym Analysis, Mutation Analysis, Bone Marrow Analysis, or could be prenatal analysis if you were high risk person (has Askenazi Jews heritaged gen)


Treatment of Gaucher Disease
Gaucher disease is treated by some methods such as Therapeutic method, Enzym replacement theraphy, Substrate reduction theraphy, etc.
1. Therapeutic methods is The major goals of treatment are elimination of symptoms, prevention of irreversible damage, and improvement in the overall health and quality of life.
2. Enzym replacement theraphy is adding enzym glucocerebroside to your body. Adverse effects of this treatment are pruritus, flushing, urticaria/angioedema, chest discomfort, respiratory symptoms, cyanosis, and hypotension. Example of this medicine is Imiglucerase (Cerezyme®), produced by recombinant DNA technology is currently marketed for use in enzyme replacement therapy for GD.
3. Substrate reduction therapy is an option when you cannot receive Enzym replacement theraphy because of its adverse effects. Example of this medicine is Miglustat (N-butyldeoxynojirimycin, NB-DNJ, OGT-918, Zavesca®), an inhibitor of glucosylceramide synthase, has been approved in the United States for restricted use in adults with GD who are medically unable to receive ERT.

Health Tips for every healthy day

1. Move Your Body, Shake More
when you move your body, you will burn the fat. Less fat, means less chance to have 'fatal illness' such as diabetes mellitus, cardiac arrest, or maybe stroke. So, shake you body, and get healthy life.

2. Less Fatty Food
Avoid the obvious such as fried foods, burgers and other fatty meats (i.e. pork, bacon, ham, salami, ribs, shrimp). I know those are delicious, but I say just avoid, don't take it everyday. So, let's say : LESS FAT, MORE HEALTH!!

3. No Smoking at All
Cigarret is poison, believe me. It has bad effects than just 'being look like masculin'. Protect yourself, and don't burn your money in front of your face.

4. Reduce Stress
Easier said than done, stress busters come in many forms. Some techniques recommended by experts are to think positive thoughts. Spend 30 minutes a day doing something you like. (i.e.,Soak in a hot tub; walk on the beach or in a park; read a good book; visit a friend; play with your dog; listen to soothing music; watch a funny movie. Get a massage, a facial or a haircut. Meditate. Count to ten before losing your temper or getting aggravated. Avoid difficult people when possible. Thought for the day: When seeing red, think pink clouds….then float on them.

5. Protect Yourself from Pollution
If you can't live in a smog-free environment, at least avoid smoke-filled rooms, high traffic areas, breathing in highway fumes and exercising near busy thoroughfares. Exercise outside when the smog rating is low. Exercise indoors in air conditioning when air quality is good. Plant lots of shrubbery in your yard. It's a good pollution and dirt from the street deterrent. Thought for the day: 'Smoke gets in your eyes'…and your mouth, and your nose and your lungs as do pollutants….hum the tune daily.

6. Wear Your Seat Belt
Statistics show that seat belts add to longevity and help alleviate potential injuries in car crashes. Thought for the day: Buckle down and buckle up.

7. Floss Your Teeth
Recent studies make a direct connection between longevity and teeth flossing. Nobody knows exactly why. Perhaps it's because people who floss tend to be more health conscious than people who don't? Thought for the day: Floss and be your body's boss.

8. Avoid Excessive Drinking
While recent studies show a glass of wine or one drink a day (two for men) can help protect against heart disease, more than that can cause other health problems such as liver and kidney disease and cancer. Thought for the day: A jug of wine should last a long time.

9. Keep a Positive Mental Outlook
There's a definitive connection between living well and healthfully and having a cheerful outlook on life. Thought for the day: You can't be unhappy when you're smiling or singing.

10. Choose Your Parents Well
The link between genetics and health is a powerful one. But just because one or both of your parents died young in ill health doesn't mean you cannot counteract the genetic pool handed you. Thought for the day: Follow these basic tips for healthy living and you can better control your own destiny.